Several lines of molecular evidence correlate with the
appearance of cancer metastasis, such as over-activation of receptor
tyrosine kinases, loss of transcriptional factors, loss of responsiveness of steroid nuclear receptors, increased energy
consumption and accumulation of drug resistant cancer cells. However,
little is known about how these metastasis associated phenomena relate
to each other, i.e. is there a core molecular mechanism that is
responsible for initiating and maintaining these metastasis correlated
Our lab is located at the University of Houston Science Center, Rm360 and 362 in the main campus of University of Houston.