Biomolecular Dynamics in a Cellular Environment



    After the successful Macromolecular Crowding meeting at the Telluride Science Research Center in July 2009, participants agreed to continue discussions on an electronic community such as WIKI that allows everyone to post new results and foster collaborations. It is expected to serve as a seed that will enable more researchers to engage in this electrifying field of biomolecular interactions, dynamics, conformations in a cell. It will also provide a platform for the general public to experience how scientists engage and foster new ideas. In a near future, the general public can even participate in research through web-enabled interfaces in which its development has been in progress at the University of Houston.

    The effects of excluded volume on protein reactions have been investigated for decades. It was Dr. Allen Minton who coined the word "Macromolecular Crowding" in 1981 to address the complex interactions in a cell. Much investigations have been focused on the excluded volume effects. However, Dr. Minton also emphasized the importance of other physico-chemical interactions that will contribute to the overall protein reactions in a cell.

    Macromolecular Crowding

    Protein interactions and dynamics in a cellular environment

    Research Groups

    If you have any questions, please email Margaret Cheung mscheung@uh.edu